On November 12, 2024, CMS published the calendar year 2025 Medicare End-Stage Renal Disease Prospective Payment System (ESRD PPS) final rule (CMS-1805-F) in the Federal Register. The 2025 ESRD final rule provides routine updates to the ESRD PPS, payment updates for renal dialysis services to individuals with acute kidney injury, and updates for the ESRD Quality Incentive Program and ESRD Treatment Choices Model. Addenda provided by CMS on the ESRD PPS provide wage index files and facility-level impact analysis. These are available at: https://www.cms.gov/medicare/payment/prospective-payment-systems/end-stage-renal-disease-esrd/esrd-payment-regulations/cms-1805-F